Will using the DUO affect the formulation of the solution?

No, it won't. It uses high pressure air to create the mist, so it won't change the formulation of the topical solution.

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Does it still seem to get the serum on my hair strands instead of my scalp? Does DUO come with the minoxidil tonic if I buy it ? Can DUO be used with own topical minoxidil? What is the key difference between the Rootique DUO (a micro-mist applicator) and a traditional derma roller? Does DUO work with oil-based solutions/ foam?